Studies on the Precursors of the Methyl Groups of Choline in Rat Liver

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Studies on the precursors of the methyl groups of choline in rat liver.

Since the original demonstrations by du Vigneaud et al. (l-4) that the methyl group of labeled methionine can be transferred intact to choline, considerable evidence has accumulated suggesting that this is not the only source of choline methyl groups. It was shown unequivocally that choline methyl groups can be synthesized de novo in germ-free rats receiving a diet devoid of methyl donors (5). ...

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ژورنال

عنوان ژورنال: Journal of Biological Chemistry

سال: 1960

ISSN: 0021-9258

DOI: 10.1016/s0021-9258(20)81339-8